Yacht Life Sciences has a vacancy for a Research Associate Pathology.

The Pathology team works together with internal project and expert groups, to guide ground-breaking new medicines from concept to the clinic. In this respect, Pathology delivers insights into target and biomarker expression in tissues to further support safety assessments, disease indication selection and mechanisms of action of therapeutic target concepts. Your team works closely to perform experiments in-house and collaborate with international contract research organizations (CRO).

As a Research Associate, Pathology, you will be part of an international Pathology team embedded within the Translational Research Group. In this role, you will help build a state-of-the-art Pathology team to support various discovery, pre-clinical and clinical programs.

Key Accountabilities 

• You work with internal research teams to develop and perform new state-of-the-art molecular pathology techniques. These techniques detect and quantify (in situ) mRNA and protein expression in normal and diseased tissues, using single/multiplex IHC, ISH (in situ hybridization) on automated platforms (Leica Bond, Ventana Discovery).
• You generate microscopic slide scans using standard bright field and fluorescence whole slide scanners and perform quantitative image analysis.
• You translate scientific questions into experimental plans and manage these into wet-lab activities.  
• You develop single and multiplex IHC/ISH tests and are responsible for experimental work, including routine tests, experiments, documentation, interpretation, and data filing.
• You support reporting of scientific results in patents, publications, regulatory documents and reports. In this respect, you design tissue analysis assays and interpret and precisely document the data.
• As part of the Translational Research group, you belong to a team of experienced Scientists and Research Associates with state-of-the-art knowledge of antibody biology, pathology and biomarkers (immuno-oncology).
• You help manage human tissue databases and downstream lab processes using the Laboratory Information Management System and digital image databases.